Vaccination Market Research | SIS International

Pesquisa de mercado de vacinação

Pesquisa e Estratégia de Mercado Internacional da SIS


A vacinação é o processo de fortalecimento do sistema imunológico. Ele permite que o sistema imunológico impeça que uma doença ou vírus entre no corpo. As injeções são o método usual para levar as vacinas ao corpo. Algumas vacinas são orais e outras são administradas pelo nariz. Quando um profissional de saúde aplica uma vacina pelo nariz, o corpo responde rapidamente e alguns profissionais consideram esse o melhor método. É muito melhor do que a resposta a outros métodos.

As vacinas também são o método mais eficaz de prevenção de doenças infecciosas. No século 20, a varíola infectou cerca de 300 milhões de pessoas. Ninguém relatou quaisquer novos casos de varíola desde 1977. Assim, em 1980, a varíola tornou-se a única doença humana erradicada na história da saúde. Essa conquista se deve à vacina contra a varíola.

Por que a pesquisa de mercado de vacinação é importante?

A vacinação é essencial porque é a forma mais rápida de combater os surtos. A Pesquisa de Mercado de Vacinação permite que os sistemas de saúde adotem a abordagem correta a estes surtos.

Por exemplo, durante a década de 1970, o governo japonês vacinou mais de três quartos de todas as crianças contra a tosse convulsa. Depois houve relatos de que a vacina não era segura e desnecessária. O número de pessoas que tomaram a vacina despencou. O surto voltou, causando milhares de casos e dezenas de mortes. Assim que a taxa de vacinação melhorou, os casos voltaram a diminuir. Portanto, não devemos encarar a vacinação levianamente.

Vaccination Market Research: How Leading Manufacturers Win Share in a Crowded Pipeline

Vaccination market research has shifted from public health forecasting to commercial intelligence shaping launch sequencing, payer negotiations, and supply commitments. The manufacturers gaining ground treat it as a continuous discipline tied to specific decisions, not a periodic exercise.

The competitive set has widened. mRNA platforms from Moderna and Pfizer-BioNTech now compete against recombinant protein approaches from Novavax and Sanofi, conjugate technologies from Merck and GSK, and viral vector candidates advancing from Janssen and Bharat Biotech. Each platform carries different cost-of-goods, cold chain demands, and payer perception. Sizing the opportunity without isolating these variables produces forecasts that collapse on contact with procurement reality.

What Modern Vaccination Market Research Measures

The strongest commercial teams treat vaccines as a B2B procurement category, not a consumer product. The buyers are ministries of health, GAVI, PAHO Revolving Fund, integrated delivery networks, and pharmacy benefit managers. Each negotiates on tiered pricing, volume guarantees, and indication breadth. Research that ignores procurement architecture produces price points the market will never accept.

Useful vaccination market research isolates four variables: indication prioritization across pediatric, adult, and travel segments; platform competitive intelligence at the antigen level; payer value story construction with HTA submission evidence; and channel economics across public tender, retail pharmacy, and physician office. The output feeds launch sequencing decisions and bill of materials negotiations with contract manufacturers.

SIS International Research has observed across vaccine engagements in North America, Europe, and Asia-Pacific that manufacturers consistently underweight the influence of pharmacy chains in adult immunization volume. CVS, Walgreens, and Boots in the UK now function as gatekeepers for influenza, shingles, and RSV uptake, and their formulary inclusion criteria differ materially from hospital systems.

Where Real-World Evidence Changes the Commercial Equation

Real-world evidence has become the asset that separates approved vaccines from reimbursed ones. NICE in the UK, IQWiG in Germany, and ICER in the United States increasingly require effectiveness data beyond pivotal trials before granting favorable positioning. Manufacturers building post-launch evidence generation into commercial planning capture price premiums others lose at the negotiation table.

The shift extends to private payers. UnitedHealthcare and Anthem now scrutinize duration of protection, breakthrough infection rates, and indirect benefits like reduced hospitalization in their coverage policies. Vaccines positioned only on seroconversion data face step-edits and prior authorization. Those positioned on outcomes data move directly to preferred status.

The opportunity sits in designing the evidence package before Phase III readout, not after. Leading commercial teams synchronize biostatistics, market access, and medical affairs around the payer questions that will define reimbursement five years out.

How KOL Mapping Drives Adoption Beyond Approval

KOL mapping in vaccines differs from oncology or rare disease. The opinion network includes ACIP voting members, JCVI advisors in the UK, STIKO experts in Germany, and CTV members in France whose recommendations drive national immunization schedules. A single recommendation from these bodies shifts commercial trajectory by orders of magnitude.

Below the policy tier sits a second network of pediatric society chairs, infectious disease department heads, and pharmacy benefit consultants who shape institutional protocols. Manufacturers mapping only the first tier miss the implementation layer where adoption stalls or accelerates.

Structured B2B expert interviews conducted by SIS with senior immunization advisors across G7 markets indicate that recommendation timing relative to procurement cycles produces larger commercial swings than the recommendation itself. A favorable position issued after annual tender awards delays revenue by a full season.

The Geographic Sequencing Decision

Launch sequencing in vaccines is a portfolio optimization problem. Markets differ on regulatory pathway, reimbursement timeline, manufacturing requirements, and competitive density. The instinct to lead in the United States often costs share in faster-converting markets like Germany, Australia, and Japan.

Mercado Primary Channel Decision Body Typical Adoption Cycle
Estados Unidos Retail pharmacy + IDN ACIP, CMS, private payers 12-18 months post-approval
Reino Unido NHS tender JCVI, NICE 18-24 months
Alemanha Statutory health funds STIKO, G-BA 6-12 months
Brasil PAHO Revolving Fund + private PNI, ANVISA 24-36 months
Japão Routine immunization program MHLW, PMDA 12-18 months

Source: SIS International Research, synthesis of vaccine market access engagements

The pattern manufacturers exploit: launch in two or three fast-conversion markets to build real-world evidence, then enter slower markets armed with effectiveness data the HTA bodies require. This sequencing produces cleaner pricing benchmarks and stronger reference price positions.

Competitive Intelligence at the Antigen Level

Vaccine competitive intelligence operates at finer resolution than most therapeutic categories. A single indication may host competitors with different valencies, adjuvant systems, and target populations. RSV illustrates the point: GSK’s Arexvy, Pfizer’s Abrysvo, and Moderna’s mResvia compete in adults over 60 with different efficacy profiles, dosing, and cold chain requirements. Sanofi and AstraZeneca’s nirsevimab competes in infants. Treating these as one market obscures the share dynamics that matter.

The same logic applies to pneumococcal, meningococcal, and HPV categories. Pfizer’s Prevnar 20 against Merck’s Vaxneuvance and Capvaxive plays out differently in pediatric versus adult segments, and differently again across public tender versus private channels. Vaccination market research that segments by valency, indication, and channel produces forecasts procurement teams trust.

The SIS Commercial Vaccine Intelligence Framework

SIS applies a four-layer framework to vaccination market research engagements:

  • Demand layer: epidemiology, indication prioritization, and patient flow modeling across public and private channels.
  • Access layer: HTA submission evidence, payer value story, and tender architecture across target geographies.
  • Camada de rede: KOL mapping across policy, institutional, and implementation tiers with influence weighting.
  • Competitive layer: antigen-level platform benchmarking, cold chain economics, and supply commitment analysis.

The framework produces decisions, not decks. Commercial teams use it to defend launch sequencing, negotiate manufacturing capacity, and structure evidence generation before pivotal readouts.

Where Commercial Vaccine Strategy Is Heading

Three forces will shape the next decade of vaccination market research. mRNA platform expansion into seasonal influenza, RSV combinations, and oncology applications will compress development timelines and intensify launch overlap. Combination vaccines, particularly respiratory triples from Moderna and Pfizer, will reshape category economics and force payer reframing. Public-private financing structures, including advance market commitments and CEPI partnerships, will alter how commercial teams forecast emerging market revenue.

Manufacturers building continuous intelligence capability across these forces will win disproportionate share. Those treating vaccination market research as episodic will keep solving last cycle’s problem.

Sobre SIS Internacional

SIS Internacional offers Quantitative, Qualitative, and Strategy Research. We provide data, tools, strategies, reports, and insights for decision-making. We also conduct interviews, surveys, focus groups, and other Market Research methods and approaches. Entre em contato conosco para o seu próximo projeto de pesquisa de mercado.

Foto do autor

Ruth Stanat

Fundadora e CEO da SIS International Research & Strategy. Com mais de 40 anos de experiência em planejamento estratégico e inteligência de mercado global, ela é uma líder global confiável em ajudar organizações a alcançar sucesso internacional.

Expanda globalmente com confiança. Entre em contato com a SIS Internacional hoje mesmo!

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